Denali Therapeutics Inc. (DNLI) shares ended the last trading session 17.7% higher at $32.12. The jump came on an impressive volume with a higher-than-average number of shares changing hands in the session. This compares to the stock's 1.8% loss over the past four weeks.Shares gained as investors are impressed by the company’s progress with its pipeline candidates. Denali possesses a notable portfolio of targeted therapeutic candidates for neurodegenerative diseases which promise potential. This company is expected to post quarterly loss of $0.83 per share in its upcoming report, which represents a year-over-year change of -20.3%. Revenues are expected to be $10.06 million, up 90.1% from the year-ago quarter.While earnings and revenue growth expectations are important in evaluating the potential strength in a stock, empirical research shows a strong correlation between trends in earnings estimate revisions and near-term stock price movements.For Denali Therapeutics Inc., the consensus EPS estimate for the quarter has remained unchanged over the last 30 days. And a stock's price usually doesn't keep moving higher in the absence of any trend in earnings estimate revisions. So, make sure to keep an eye on DNLI going forward to see if this recent jump can turn into more strength down the road.The stock currently carries a Zacks Rank #3 (Hold). You can see the complete list of today's Zacks Rank #1 (Strong Buy) stocks here >>>>Denali Therapeutics Inc. belongs to the Zacks Medical - Biomedical and Genetics industry. Another stock from the same industry, Zymeworks Inc. (ZYME), closed the last trading session 1.3% higher at $5.58. Over the past month, ZYME has returned -14.2%.Zymeworks Inc.'s consensus EPS estimate for the upcoming report has remained unchanged over the past month at -$0.86. Compared to the company's year-ago EPS, this represents a change of +31.2%. Zymeworks Inc. currently boasts a Zacks Rank of #3 (Hold). FREE Report: The Metaverse is Exploding! Don’t You Want to Cash In? Rising gas prices. The war in Ukraine. America's recession. Inflation. It's no wonder why the metaverse is so popular and growing every day. Becoming Spider Man and fighting Darth Vader is infinitely more appealing than spending over $5 per gallon at the pump. And that appeal is why the metaverse can provide such massive gains for investors. But do you know where to look? Do you know which metaverse stocks to buy and which to avoid? In a new FREE report from Zacks' leading stock specialist, we reveal how you could profit from the internet’s next evolution. Even though the popularity of the metaverse is spreading like wildfire, investors like you can still get in on the ground floor and cash in. Don't miss your chance to get your piece of this innovative $30 trillion opportunity - FREE.>>Yes, I want to know the top metaverse stocks for 2022>>Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report Denali Therapeutics Inc. (DNLI): Free Stock Analysis Report Zymeworks Inc. (ZYME): Free Stock Analysis Report To read this article on Zacks.com click here. Zacks Investment Research