AstraZeneca plc AZN announced that Japan’sMinistry of Health, Labour and Welfare (MHLW) has granted approval to expand the label of Forxiga for the treatment of chronic heart failure with reduced ejection fraction (HFrEF) in adults with and without type-II diabetes (T2D). The sNDA was based on positive results from the DAPA-HF phase III study on Farxiga.Data from the DAPA-HF study showed that Forxiga, in addition to standard of care, reduced the risk of the composite outcome versus placebo by 26%.Forxiga was approved in EU fora similar label expansion last month and in the United States in May 2020.This year so far, AstraZeneca’s shares have risen 9.4% compared with an increase of 4.9% for the industry. Several outcomes studies are ongoing on Farxiga for heart failure indications and chronic kidney disease (CKD) indications under the DapaCare clinical program. DAPA-HF is part of the DapaCare program. Farxiga (Forxiga’s name in United States) is being studied in the DELIVER study to evaluate its effect on patients with heart failure (HF) with preserved ejection fraction (HFpEF). DAPA-MI study is evaluating patients without T2D following an acute myocardial infarction (MI) or heart attack. DAPA-CKD has been conducted in patients with CKD.Farxiga/Forxiga, a key top-line driver of AstraZeneca, generated sales worth $1.38 billion in the nine months of 2020, representing 26% growth at constant exchange rates. Farxiga enjoys global leadership with a significant market share.Other SGLT2 inhibitors available in the market are Johnson & Johnson’s JNJ Invokana and Lilly’s LLY and Boehringer Ingelheim's Jardiance. Another successful diabetes medicine, which is not a SGLT2 drug, is Novo Nordisk’s NVO GLP-1 drug, Victoza.AstraZeneca currently carries a Zacks Rank #3 (Hold). You can see the complete list of today’s Zacks #1 Rank (Strong Buy) stocks here.Legal Marijuana: An Investor’s DreamImagine getting in early on a young industry primed to skyrocket from $17.7 billion in 2019 to an expected $73.6 billion by 2027. Although marijuana stocks did better as the pandemic took hold than the market as a whole, they’ve been pushed down. This is exactly the right time to get in on selected strong companies at a fraction of their value before COVID struck. Zacks’ Special Report, Marijuana Moneymakers, reveals 10 exciting tickers for urgent consideration.Download Marijuana Moneymakers FREE >>Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report Johnson & Johnson (JNJ): Free Stock Analysis Report Novo Nordisk AS (NVO): Free Stock Analysis Report AstraZeneca PLC (AZN): Free Stock Analysis Report Eli Lilly and Company (LLY): Free Stock Analysis Report To read this article on Zacks.com click here. Zacks Investment Research