Mirati Therapeutics MRTX stock was up 11.3% on Wednesday on reports that big cancer drugmakers may offer to buy the company ahead of some upcoming important company milestones.However, in the year so far, the stock price of Mirati has plunged 34.7% compared with the industry’s decline of 19.5%.Image Source: Zacks Investment ResearchMirati’s new drug application (NDA), seeking approval for adagrasib, its KRAS inhibitor drug, for previously-treated KRASG12C-mutated non-small cell lung cancer (NSCLC) is under review with the FDA. A decision by the FDA is expected by Dec 14, 2022. A marketing authorization application (MAA) is also under review in Europe. Both the NDA and the MAA are based on data from the phase II registration-enabling cohort of the KRYSTAL-1 study. If adagrasib is approved and can outperform any potential competitor from the same class, it will be a huge boost to the stock. This is the primary reason for attracting promising buyout offers.Potential buyers could be Pfizer, Bristol-Myers BMY, Merck MRK or AstraZeneca, per an article on Investor's Business Daily. Mirati did not issue any press release or make any comment on the buyout speculations. There are currently no formal offers and a deal is not imminent.Mirati is also evaluating adagrasib — both as monotherapy and combinations — in multiple cohorts of phase I/II KRYSTAL-1 study across multiple solid tumors that harbor KRAS G12C mutations. These include a combination of adagrasib with Merck’s Keytruda in NSCLC, adagrasib plus Boehringer Ingelheim’s Gilotrif (afatinib) in advanced NSCLC and adagrasib with Bristol-Myers’ Erbitux (cetuximab) in advanced colorectal cancer or CRC. Top-line interim data from another study, KRYSTAL-7 study evaluating adagrasib plus Merck’s Keytruda in first-line NSCLC is expected to be released in the fourth quarter. If the data are positive, it can further increase interest in Mirati.Adagrasib, if approved, will face competition from Amgen’s AMGN KRAS G12C inhibitor, Lumakras, which was approved for second-line NSCLC in the United States in 2021 and in Europe in January 2022. It is now launched in more than 45 countries. Amgen’s Lumakras is off to an excellent start, while its label expansion studies, which have the potential to significantly expand the currently addressable patient population, are progressing rapidly.Mirati’s other pipeline candidate, sitravatinib, is being evaluated in a pivotal phase III study (SAPPHIRE) combined with Bristol-Myers’ Opdivo for second-line or third-line non-squamous NSCLC. Interim data from the study is expected in the fourth quarter of 2022. If the outcome turns out to be positive, it could be the basis of regulatory submissions for sitravatinib in the United States and Europe, potentially by mid-2023.Zacks RankMirati currently has a Zacks Rank #3 (Hold). You can see the complete list of today’s Zacks #1 Rank (Strong Buy) stocks here. Free Report Reveals How You Could Profit from the Growing Electric Vehicle Industry Globally, electric car sales continue their remarkable growth even after breaking records in 2021. High gas prices have fueled his demand, but so has evolving EV comfort, features and technology. So, the fervor for EVs will be around long after gas prices normalize. Not only are manufacturers seeing record-high profits, but producers of EV-related technology are raking in the dough as well. Do you know how to cash in? If not, we have the perfect report for you – and it’s FREE! Today, don't miss your chance to download Zacks' top 5 stocks for the electric vehicle revolution at no cost and with no obligation.>>Send me my free report on the top 5 EV stocksWant the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report Bristol Myers Squibb Company (BMY): Free Stock Analysis Report Merck & Co., Inc. (MRK): Free Stock Analysis Report Amgen Inc. (AMGN): Free Stock Analysis Report Mirati Therapeutics, Inc. (MRTX): Free Stock Analysis ReportTo read this article on Zacks.com click here.Zacks Investment Research